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ASMARA: Antimicrobial Stewardship Mobile Application in Reducing AMR (Antimicrobial Resistance)

25 Apr 2022

ASMARA: Antimicrobial Stewardship Mobile Application in Reducing AMR (Antimicrobial Resistance)

Project leader: Ms Thresia Maria Wonga

Level of education and university: Master, The University of Adelaide

Collaborating Organisations: Prof Dr W Z Johannes Kupang General Teaching Hospital

Project Location: Nusa Tenggara Timur

Activity Type: Knowledge and technology transfer

Sector: -

Project Rationale:

Antimicrobial Resistance (AMR) is one of the 21st century’s greatest global health threats. It became a global health emergency in May 2015. Basically, AMR happens because of selection pressure regarding Antimicrobial Use (AMU), due to the inappropriate prescribing of antibiotics, such as overuse and misuse, and the spread of bacteria resistance. In Indonesia, the use of antimicrobials wisely and qualitatively optimal is merely 20% (Ministry of Health, 2016).

AMR, moreover, has an impact in increasing the death rate and disability rate, threatening modern medicines, maternal and child health, as well as health expenditure with regards to GDP. The COVID-19 crisis also would further fuel the trend (WHO,2021), as most hospitalised COVID-19 patients globally receive antibiotics. Conversely, there has been less clinical development of new antimicrobials since 1987.

I have been working for two decades at Prof Dr W Z Johannes Kupang General Teaching Hospital. As a big referral hospital with complex infectious cases, it has been shown that there has been an unrecognised increasing number in the AMU, especially the “watch” category in the last decade. This category, however, should be used carefully only to a limited group of well-defined syndromes and closely monitored.

At the patient level, antimicrobial prescribers need a complex sequence of clinical decisions. Besides there is a lack of guidelines available for timely diagnosis, prescribing unnecessary and ineffective antibiotics is a common phenomenon in most public hospitals. Less understanding about antimicrobials uses and resistance is one of key driven of the phenomenon. Guidelines, workshops and Antimicrobials Stewardship Programs (ASP), for example, are recommended for optimising antibiotics use and microorganism resistance which will be useful in reducing cost as well as maintaining quality of care by supporting clinical decisions.

Electronic Decision Support Systems (eDSSs), however, might support and improve a complex task in the Antimicrobials Stewardship Programs (ASP). An effective eDSSs does not have to be complex. It might include accessible online documents such as antibiotic guidelines, restrictive indication, antimicrobial prescribing principle, dosing, contraindications, administration of antibiotics, interaction etc. Therefore, it is pivotal to develop ASMARA as a form of eDSSs and conduct a workshop during 2022 World Antimicrobial Awareness Week in November.

Project Beneficiaries:

There are several parties that benefit from this project:

  • Around 1,502 clinicians, general practitioners and pharmacists in East Nusa Tenggara (Provincial Health Agency, 2018), might be users of ASMARA, including 673 who work in a host hospital. The user-friendly app will provide antimicrobial use related guidelines which support clinical decisions in infectious treatment be more accurate and time efficient.
  • 150 health practitioners, including those who work in the Hospital Antimicrobial Resistance (AMR) control program team, either from the host hospital or city/district hospital in East Nusa Tenggara, will gain knowledge about the AMS program during the 2-days workshop during the World Antimicrobial Awareness Week (WAAW) 2022.
  • 15,396 nurses and midwives, including 549 nurses and midwives in Prof Dr W Z Johannes Kupang General Teaching Hospital, who need ASMARA to assist their care, such as dosing/ Creatinine Clearance/vancomycin/ gentamicin calculator, administration of antibiotic, antimicrobial/penicillin allergy, interactions, IV-to-Oral switching recommendations, antibiotics in pregnancy, new born and pediatric and antimicrobials in renal impairment, besides antibiotics use and surgical prophylaxis guidelines.
  • 52 hospitals in East Nusa Tenggara might utilise ASMARA as antimicrobial digital guidelines, which probably reduce inappropriate use of antimicrobials, antimicrobial expenses, total medicines expenditure, and hospitalisation cost.
  • Patients with infectious disease will have better quality of antimicrobial treatment.

Priority Development Area:

Health Security

Link with Australian organisation:

Flinders Overseas Health Group (FOHG)

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